3,4-diarylisoxazol-5-acetic acids

Details 3,4-diarylisoxazol-5-acetic acids 3,4-diarylisoxazol-5-acetic acids

C - Chemistry, Metallurgy

07

D

260/311.9

C07D 261/08 (2006.01)

Patent

CA 1128526

CONL-41 3,4-DIARYLISOXAZOL-5-ACETIC ACIDS Abstract of the Disclosure 3,4-Diarylisoxazol-5-acetic acids of the formula Image 1 in which Ar1 and Ar2 are the same or different and are selected from phenyl and naphthyl, R1, R2, R3, and R4 are the same or different and are selected from hydrogen, halogen, trifluoromethyl, lower alkyl, and lower alkoxy, and R5 is selected from hydrogen, lower alkyl, and lower alkoxy. The compounds have anti-inflammatory, analgesic, and anti-pyretic activities and a low order of toxicity, and methods for their preparation and use are also disclosed.

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