A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4985 (2006.01) A61K 31/42 (2006.01) A61K 31/5383 (2006.01) A61P 11/02 (2006.01) A61P 25/24 (2006.01) A61P 27/06 (2006.01) A61P 29/00 (2006.01) C07D 403/06 (2006.01) C07D 413/06 (2006.01) C07D 413/14 (2006.01) C07D 417/06 (2006.01) C07D 471/04 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2677678
The present invention relates to a novel class of phenylmorpholine and phenyl thiomorpholine compounds useful as alpha2C adrenergic receptor agonists, pharmaceutical compositions containing the compounds, and methods of treatment, prevention, inhibition,- or amelioration of one or more diseases associated with the alpha2C adrenergic receptor agonists, such as allergic rhinitis, congestion, pain, diarrhea, glaucoma, congestive heart failure, cardiac ischemia, manic disorders, depression, anxiety and schizophrenia.
L'invention concerne, dans ses nombreux modes de réalisation, une nouvelle catégorie de composés phénylmorphiline et phénylthiomorpholine utiles en tant qu'agonistes du récepteur adrénergique a2C, des compositions pharmaceutiques contenant les composés et des procédés de traitement, de prévention, d'inhibition ou d'amélioration d'une ou plusieurs pathologies associées aux agonistes du récepteur adrénergique a2C utilisant ces composés ou compositions pharmaceutiques.
Aslanian Robert G.
Boyce Christopher W.
de Lera Ruiz Manuel
Fevrier Salem
Guise Zawacki Lisa
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Pharmacopeia Llc
Schering Corporation
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