3,4-dihydro-2h-benzo¬1,4|oxazinyl-methyl¬3-(1h-indol-3-yl)-a...

Details 3,4-dihydro-2h-benzo¬1,4|oxazinyl-methyl¬3-(1h-indol-3-yl)-a... 3,4-dihydro-2h-benzo¬1,4|oxazinyl-methyl¬3-(1h-indol-3-yl)-a...

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/538 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2355308

Compounds are provided which have formula (1) wherein: R is hydrogen, alkyl of 1 to 6 carbon atoms, phenyl, or substituted phenyl; X and Y are each, independently, hydrogen, halogen, cyano, or alkoxy of 1 to 6 carbon atoms; and m is 1 to 5; or a pharmaceutically acceptable salt thereof useful in the treatment of neurological diseases caused by disorders of the serotonin- affected neurological systems.

L'invention concerne des composés de formule (1) dans laquelle R est hydrogène, un alkyle contenant de 1 à 6 atomes de carbone, un phényle ou un phényle substitué; X et Y sont chacun, indépendamment, hydrogène, halogène, cyano ou alcoxy contenant de 1 à 6 atomes de carbone; et m est compris entre 1 et 5; ou un sel pharmaceutiquement acceptable de ces composés, utile pour traiter des affections neurologiques causées par des troubles des systèmes neurologiques, influencés par la sérotonine.

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