3,4-dihydro-5-(pyridinyl or hydroxyphenyl)-2(1h)-...

Details 3,4-dihydro-5-(pyridinyl or hydroxyphenyl)-2(1h)-... 3,4-dihydro-5-(pyridinyl or hydroxyphenyl)-2(1h)-...

C - Chemistry, Metallurgy

07

D

260/294.1, 260/2

C07D 211/86 (2006.01) C07D 213/55 (2006.01) C07D 213/57 (2006.01) C07D 213/64 (2006.01) C07D 401/04 (2006.01)

Patent

CA 1195980

ABSTRACT OF THE DISCLOSURE 3,4-Dihydro-3-R1 -4-R2-5-Q-6-R-2(III)-pyridinones (1), where R1 and R2 are each hydrogen or methyl, R is lower-alkyl and Q is 4 (or 3)-hydroxyphenyl, 4 (or 3)-methoxyphenyl, 4 (or 3)-pyridinyl or 4 (or 3)-pyridinyl having one or two lower-alkyl substituents, or acid-addition salts thereof, and their preparation are shown. Also shown is the cardiotonic use of I where Q is 4 (or 3)-hydroxyphenyl, 4 (or 3)-pyridinyl or 4 (or 3)-pyridinyl having one or two lower- alkyl substituents.

441427

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