3,4-dihydro-5h-2,3-benzodiazepine derivatives and a process...

Details 3,4-dihydro-5h-2,3-benzodiazepine derivatives and a process... 3,4-dihydro-5h-2,3-benzodiazepine derivatives and a process...

C - Chemistry, Metallurgy

07

D

260/239.7

C07D 243/02 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 1178584

ABSTRACT The invention relates to new 3,4-dihydro- -5H-2,3-benzodiazepine derivatives of the general formula (I) and pharmaceutically acceptable acid addition salts thereof. Image wherein R represents a phenyl group optionally carrying one or two substituents selected from the group consisting of halogen, hydroxy, C1-4 alkoxy and benzyloxy; a furyl or a thienyl group, R1 stands for a hydrogen atom or a C1-4 alkyl group, R2 and R3 each represent hydrogen atom, C1-4 alkoxy, C4-7 cycloalkoxy or benzyloxy group. The new compounds of the general formula (I) can be prepared by reducing a 5H-2,3-benodiazepine derivative of the general formula (II) Image (II) wherein R, R1, R2 and R3 have the above-defined meanings, with an inorganic or organic hydride and and complex metal hydride. The new compounds of the general formula (I) possess significant cent- ral nervous effects and can advantageously be used in the therapy.

398115

Affiliated with

Also associated with

Rating

3,4-dihydro-5h-2,3-benzodiazepine derivatives and a process... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3,4-dihydro-5h-2,3-benzodiazepine derivatives and a process..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3,4-dihydro-5h-2,3-benzodiazepine derivatives and a process... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1329654