3,4-substituted pyrrole derivatives

Details 3,4-substituted pyrrole derivatives 3,4-substituted pyrrole derivatives

C - Chemistry, Metallurgy

07

D

260/316, 260/280

C07D 207/34 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01)

Patent

CA 1206966

ABSTRACT OF THE DISCLOSURE This invention relates to novel pyrrole derivatives of the general formula II' Image II' wherein R1 is a fragment selected from the group consisting of [X,Y,Z(phenyl)], [X,Y,Z(biphenyl)l, [U,V,W(pyridyl)], [U,V,W(furyl)] and [U,V,W(thienyl)], wherein X, Y and Z are each independently selected from the group consisting of hydrogen, halogen, C1-C4alkyl, Cl-C3haloalkyl, di(Cl- C4alkyl)amino, nitro, cyano, -COO(Cl-C4alkyl), -CON(Cl- C4alkyl)2 and the group -E-R4, where E is -O-, -S-, -SO- or -SO2-, R4 is Cl-C6alkyl which is unsubstituted or sub- stituted by C1-C4alkoxy, C3-C5alkenyl which is unsub- stituted or substituted by halogen, C3-C5alkyoyl which is unsubstituted or substituted by halogen or hydroxy, or is [X,Y,Z(phenyl)] or -CH2-[X,Y,Z(phenyl)]; U, V and W are each independently selected from the group consisting of hydrogen, halogen and Cl-C4alkyl, and R2 is -COO(Cl-C6alkyl), -CO(Cl-C6alkyl), -CO-N(C1-C6alkyl)2, cyano, nitro, -SO2-(Cl-C6alkyl), -P(O)-(C1-C6alkoxy)2, -SO-(Cl-C6alkyl) or -SO2-N(Cl-C3alkyl)2. These compounds are useful intermediates in the preparation of certain correspond- ing N-sulfenylated pyrrole derivatives having microbicidal activity.

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