3-(5-aminopentyl)-amino-1-benzazepin-2-one-1-alkanoic acids

Details 3-(5-aminopentyl)-amino-1-benzazepin-2-one-1-alkanoic acids 3-(5-aminopentyl)-amino-1-benzazepin-2-one-1-alkanoic acids

C - Chemistry, Metallurgy

07

D

260/241.4

C07D 223/16 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1225397

3-(5-Aminopentyl)-amino-1-benzazepin-2-one-1-alkanoic acids Abstract of to disclosure The invention concerns angiotensin-converting enzyme inhibitors of the formula I Image (I) wherein R1 represents 4-aminobutyl, R2 and R3 represent, indepen- dently of each other, hydroxy or lower alkoxy and S represents the chirality; and salts thereof. They are prepared, for example, by reducing a starting material corresponding to formula I, which contains a double bond located at the carbon atom in 3-position.

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