3,5-aryl, heteroaryl or cycloalkyl...

A - Human Necessities – 61 – K

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A61K 31/4245 (2006.01) C07D 271/06 (2006.01)

Patent

CA 2539438

The present invention encompasses compounds of Formula I: (I) as well as the pharmaceutically acceptable salts thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.

L'invention concerne des composés représentés par la formule I ainsi que les sels pharmaceutiquement acceptables de ces composés. Lesdits composés servent au traitement de maladies et de troubles d'origine immunologique tels que les rejets de greffe de moelle osseuse, d'organes et de tissus. L'invention concerne également des compositions pharmaceutiques et des procédés d'utilisation de ces compositions.

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