C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/33 (2006.01) C07C 229/36 (2006.01) C07C 231/02 (2006.01) C07C 237/20 (2006.01) C07C 255/13 (2006.01) C07C 271/16 (2006.01) C07C 271/18 (2006.01) C07C 271/22 (2006.01) C07D 241/08 (2006.01) C07D 263/26 (2006.01) C07D 295/13 (2006.01) C07D 405/06 (2006.01) C07D 407/06 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07D 413/14 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2147052
Compounds of formula I (I), Image wherein R1 is free or esterified carboxy, hydroxymethyl or formyl, R2 and R4 are each independently of the other aliphatic, cycloaliphatic-aliphatic, araliphatic or heteroarylaliphatic radicals and R3 is azido, or amino that is aliphatically or araliphatically substituted and/or protected by an amino-protecting group, and the salts thereof, are valuable intermediates in the preparation of medicinal active ingredients, for example of compounds of formula II Image (IIa), Image (IIb), wherein RA is an aromatic or heteroaromatic radical, R2 and R4 are each independently of the other aliphatic, cycloaliphatic, cycloaliphatic- aliphatic or araliphatic radicals, R3 is unsubstituted or N-mono- or N,N-di-lower alkylated or N-lower alkanoylated amino, and R8 is an aliphatically, cycloaliphatically or heteroaromatically-aliphatically substituted amino group, and the salts thereof, which can be used, for example, as antihypertensives.
Goschke Richard
Herold Peter
Maibaum Jurgen Klaus
Rigollier Pascal
Fetherstonhaugh & Co.
Novartis Ag
LandOfFree
3,5-disubstituted tetrahydrofuran-2-ones does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 3,5-disubstituted tetrahydrofuran-2-ones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3,5-disubstituted tetrahydrofuran-2-ones will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2018514