C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/40 (2006.01) A61K 31/415 (2006.01) A61K 31/4155 (2006.01) A61K 31/4178 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/5377 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2380786
3-ureido-pyrazole derivatives represented by formula (I): where R, R1 and R2 are as described herein, or pharmaceutically acceptable salts thereof; are useful, for example, for the treatment of cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases or neurodegenerative diseases.
Cette invention concerne des dérivés de 3-uréido-pyrazole représentés par la formule (I) dans laquelle R, R¿1? and R¿2? sont tels qu'explicités dans le descriptif ou bien sont des sels de ces dérivés. Lesdits dérivés conviennent, par exemple, pour le traitement du cancer, de pathologies dues à une prolifération cellulaire, de la maladie d'Alzheimer, d'infections virales, de maladies auto-immunes ou d'affections maladies neurovégétatives.
Fritzen Edward L.
Orsini Paolo
Pevarello Paolo
Pierce Betsy S.
Traquandi Gabriella
Pharmacia & Upjohn Company
Pharmacia & Upjohn S.p.a.
Smart & Biggar
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