3, 6-bicyclolides

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2587788

The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof (I), which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

Composés de formule (I) ou sels, esters ou promédicaments desdits composés acceptables sur le plan pharmaceutique, qui présentent des propriétés antibactériennes. La présente invention concerne également des compositions pharmaceutiques contenant les composés susmentionnés et destinées à être administrées à un sujet nécessitant un traitement antibiotique. La présente invention concerne en outre des méthodes de traitement d'une infection bactérienne chez un sujet par administration d'une composition pharmaceutique contenant les composés selon la présente invention. Elle concerne enfin un procédé permettant de produire les composés selon la présente invention.

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