3,6-ketal and enol ether macrolide antibiotics

Details 3,6-ketal and enol ether macrolide antibiotics 3,6-ketal and enol ether macrolide antibiotics

C - Chemistry, Metallurgy

07

H

C07H 17/00 (2006.01) A61K 31/70 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2263203

This invention relates to compounds of formulas 1 and 2 Image Image and to pharmaceutically acceptable salts and solvates thereof, wherein X, X1, R1, R2, R7, R17 and R19 are as defined herein. The compounds of formulas 1 and 2 may be useful in the treatment of bacterial, parasitic and protozoal infections, as well as disorders related to bacterial, parasitic and protozoal infections, in mammals, fish and birds. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and 2 and to methods of treating bacterial, parasitic and protozoal infections by administering the compounds of formula 1 and 2.

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