3-(6-quinolylmethyl)-4h-imidazol-4-one derivatives, their...

Details 3-(6-quinolylmethyl)-4h-imidazol-4-one derivatives, their... 3-(6-quinolylmethyl)-4h-imidazol-4-one derivatives, their...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2111302

3-(6-QUINOLYLMETHYL)-4H-IMIDAZOL-4-ONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY SYNTHELABO An invention of: Gérard CREMER, Jean-Claude MULLER Abstract 3-(6-Quinolylmethyl)-4H-imidazol-4-one deriva- tives corresponding to the formula (I): (I) Image in which R1 represents an unbranched or branched (C2-C5)alkyl group, R2 and R3 represent, each independently of one another, either a hydrogen atom, or an unbranched or branched (C1- C5)alkyl qroup, or a (CH2)n-aryl group where n = 0 to 3, or R2 and R3 with the imidazole ring can form a spiro- cyclo(C3-C8)alkyl group, as well as their addition salts with pharmaceutically acceptable acids and bases. Therapeutic application.

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