C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/231, 260/273
C07D 471/08 (2006.01) A61K 31/445 (2006.01) C07D 471/10 (2006.01)
Patent
CA 1254209
ABSTRACT OF THE DISCLOSURE Novel 3,7-diaza bicyclo-(3,3,1)-monane compounds of formula I Image I in which the substituents R1, R2, R3, R4, Z1, and Z2 indicate the substituents as they are given in the description of the invention, as well as processes of producing said compounds, pharmaceutical compositions containing certain specific compounds of Formula I in which the substituents Z1 and Z2 are hydrogen, and methods of preparing and using said compositions are described. These compounds are characterized by an especially favourable relation between anti-arrhythmic activity or prolongation of the cardian refractory period and negative inotropic side effects.
436831
Buschmann Gerd
Hachmeister Bernd
Kehrbach Wolfgang
Kuhl Ulrich
Schoen Uwe
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Solvay Pharmaceuticals Gmbh
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