3-(7'-oxo-1'-aza-4'-oxabicyclo¬3.2.0| hept-3'-yl) propionic...

C - Chemistry – Metallurgy – 07 – D

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C07D 503/00 (2006.01) A61K 31/42 (2006.01) A61K 31/695 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2136042

A derivative of 3- (7 '-oxo-1 ' -aza-4 ' - oxabicyclo [3.2.0] hept-3'-yl)propionic acid represented by the formula Image (I) wherein R1 is a hydrogen atom, a lower alkyl group optionally having one or more cycloalkyl groups, a lower acyl group, a benzoyl group optionally having one or more substituents or a benzyl. group optionally having one or more substituents, R2 is a hydrogen atom or a carboxyl-protecting group, R3 is a hydroxyl group, an azido group, a benzenesulfonyloxy group optionally having one or more substituents, a lower alkylsulfonyloxy group optionally having one or more substituents, a tri-substituted silyloxy group or an amino group optionally having one or more substituents, provided that when R1 and R2 are hydrogen atoms, R3 is not an amino group, and a salt thereof.

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