3.8-dialkylxanthines, processes for their preparation,...

C - Chemistry – Metallurgy – 07 – D

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260/242.4

C07D 473/06 (2006.01) C07D 239/545 (2006.01)

Patent

CA 1156229

ABSTRACT The invention refers to compounds having activity against chronic obstructive airway disease or cardiovascular disease, characterized by the formula Image wherein R1 is ethyl, n-propyl, n-butyl, isobutyl, n-pentyl, 2-methylbutyl, 2,2-dimethylpropyl, cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl- methyl, and R2 is methyl, ethyl, n-propyl, isopropyl, cyclopropyl, n-butyl, isobutyl, tert. butyl or cyclobutyl provided that R1 is ethyl when R2 is methyl, or a physiologically acceptable salt thereof. The invention also refers to processes for the preparation of these compounds, a pharmaceutical preparation containing one of the compounds and a method for the treatment of chronic obstructive airway disease and cardiovascular disease.

373230

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