3,9-diazabicyclo (3.3.1) nonan-7-yl derivatives, process and...

Details 3,9-diazabicyclo (3.3.1) nonan-7-yl derivatives, process and... 3,9-diazabicyclo (3.3.1) nonan-7-yl derivatives, process and...

C - Chemistry, Metallurgy

07

D

C07D 471/08 (2006.01) A61K 31/495 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2092431

Compounds of formula (I) wherein X is a phenyl group or a monocyclic 5 or 6 membered heteroaryl group, either of which group is optionally fused to a saturated or unsaturated 5-7 membered carbocyclic or heterocyclic ring; A is linking moiety; Z is C1-6 alkyl, C3-8 cycloalkyl, C3-8 cycloalkyl C1-4 alkyl, phenyl, naphthyl, phenyl C1-4 alkyl or naphthyl C1-4 alkyl wherein a phenyl or naphthyl moiety is optionally substituted by one or more of halo, C1- 6 alkoxy or C1-6 alkyl; R is hydrogen or me- thyl having 5-HT3 receptor antagonist activity.

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