3-acylamino-2-oxo-1-azetidinyl esters of phosphonic acids,...

Details 3-acylamino-2-oxo-1-azetidinyl esters of phosphonic acids,... 3-acylamino-2-oxo-1-azetidinyl esters of phosphonic acids,...

C - Chemistry, Metallurgy

07

D

167/208, 260/300

C07D 205/085 (2006.01) A61K 31/395 (2006.01) C07F 9/568 (2006.01)

Patent

CA 1262134

ABSTRACT Antimicrobial activity is exhibited by .beta.-lactams having the formula: Image or a pharmaceutically acceptable salt thereof, wherein R1 is an acyl substituent, Y is oxygen or sulfur and R5 is hydroxyl, alkyl, substituted alkyl, phenyl, sub- stituted phenyl, alkoxy, alkylthio, (substituted al- kyl)oxy, (substituted alkyl)thio, phenyloxy, phenyl- thio, (substituted phenyl)oxy or (substituted phenyl)- thio.

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