3-alkyl-5-(2-hydroxy-styryl)-isoxazoles and their preparation

Details 3-alkyl-5-(2-hydroxy-styryl)-isoxazoles and their preparation 3-alkyl-5-(2-hydroxy-styryl)-isoxazoles and their preparation

C - Chemistry, Metallurgy

07

D

260/311.9

C07D 261/08 (2006.01) C07C 41/22 (2006.01) C07C 43/12 (2006.01) C07C 45/70 (2006.01) C07C 47/565 (2006.01) C07F 9/653 (2006.01)

Patent

CA 1128525

O.Z. 0050/033158 ABSTRACT OF THE DISCLOSURE: 3-Alkyl-5-(2-hydroxy-styryl)- isoxazoles of the general formula (1) Image (1) where R is alkyl of 1 to 4 carbon atoms, and processes for their preparation. The novel compounds of the formula (1) are valuable intermediates for the synthesis of drugs; in particular, alkylamino-hydroxypropyl-ethers of these intermediates can be used for the treatment of hypertonia, of coronary diseases of the heart and of cardiac arrhythmias.

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