(3-alkylamino-2-hydroxypropoxy)-furan-2- carboxylic acid...

Details (3-alkylamino-2-hydroxypropoxy)-furan-2- carboxylic acid... (3-alkylamino-2-hydroxypropoxy)-furan-2- carboxylic acid...

C - Chemistry, Metallurgy

07

D

260/363.5

C07D 307/34 (2006.01) C07D 307/54 (2006.01) C07D 307/68 (2006.01) C07D 307/71 (2006.01)

Patent

CA 1146953

- 25 - ABSTRACT "(3-ALKYLAMINO-2-HYDROXYPROPOXY)-FURAN-2-CARBOXYLIC ACID ANILIDES AND PHYSIOLOGICALLY TOLERATED ACID ADDITION SALTS THEREOF, PROCESSES FOR THEIR PREPARATION, AND MEDICAMENTS CONTAINING THEM" (3-Alkylamino-2-hydroxypropoxy)-furan-2- carboxylic acid anilides of the formula: Image in which R1 denotes a straight or branched C1 to C5 alkyl group or a cyclopropyl or cyclopentyl group, R2 denotes a hydrogen or halogen atom or a methyl, methoxy, nitro or acetyl group, R3 denotes a hydrogen or halogen atom or a nitro group and A denotes a single bond or the -CH2- or -CH=CH- group, and physiologically tolerated acid addition salts thereof possess .beta.-adrenolytic properties and a low toxicity.

350002

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