3-amino-1-arylpropyl indoles as monoamine reuptake inhibitor

Details 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitor 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitor

C - Chemistry, Metallurgy

07

D

C07D 209/04 (2006.01) A61K 31/4045 (2006.01)

Patent

CA 2569238

Compounds of formula I: or pharmaceutically acceptable salts thereof, wherein p, Ar, R1, R2, R3, Ra, Rb, Rc, Rd and Re are defined herein, pharmaceutical compositions containing them and methods of using them for the preparation of medicaments for treating depression or anxiety.

L'invention porte sur des composés de formule (I) ou sur leurs sels acceptables d'un point de vue pharmaceutique, formule dans laquelle p, Ar, R<1>, R<2>, R<3>, R<a>, R<b>, R<c>, R<d> et R<e> sont tels que définis dans le descriptif. L'invention porte également sur des compositions pharmaceutiques contenant ces composés et leurs méthodes d'utilisation dans la préparation de médicaments destinés à traiter la dépression ou l'anxiété.

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