3-amino-2-arylpropyl azaindoles and uses thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/04 (2006.01) A61K 31/395 (2006.01) A61K 31/437 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) C07D 487/04 (2006.01) C07D 487/14 (2006.01)

Patent

CA 2632284

The present invention provides compounds of the formula I: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein p, Ar, R1, R2, R3, Ra, Rb, Rc, Rd and Re are defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds. The compounds are useful for the treatment of diseases associated with monoamine reuptake inhibitors.

La présente invention concerne des composés de formule I : ou des sels, solvates ou promédicaments pharmaceutiquement acceptables de ces composés ; p, Ar, R1, R2, R3, Ra, Rb, Rc, Rd et Re étant définis dans le présent document. L~invention concerne également des compositions pharmaceutiques, ainsi que des procédés d~utilisation et de fabrication de ces composés. Ces composés sont utiles pour le traitement de maladies associées aux inhibiteurs du recaptage de la monoamine.

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