C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 243/08 (2006.01) A61K 31/551 (2006.01) A61P 3/04 (2006.01) A61P 17/10 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2716250
The present invention provides compounds of Formula (I) that are useful for modulating the biological activity of the melanocortin-5 receptor (MC5R). Compounds of this invention can be used to treat diseases and/or conditions in which down-regulation of MC5R is beneficial. Such diseases and/or conditions include, but are not limited to, acne, seborrhea, seborrheic dermatitis, cancer, and inflammatory diseases.
La présente invention concerne des composés de formule (I) utiles pour la modulation de l'activité biologique du récepteur 5 de la mélanocortine (MC5R). Les composés de l'invention peuvent être utilisés pour traiter des maladies et/ou pathologies dans lesquelles la régulation négative du MC5R est avantageuse. Ces maladies et/ou pathologies comprennent, mais pas exclusivement, l'acné, la séborrhée, la dermatite séborrhéique, le cancer et les maladies inflammatoires.
Blaskovich Mark Arnold Thomas
Cassidy Peter Joseph
Mimetica Pty Ltd
Sim & Mcburney
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