3-aminocarbonylmethoxy-5-phenylpyrazole compounds, method of...

C - Chemistry – Metallurgy – 07 – D

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C07D 231/46 (2006.01) C07D 231/20 (2006.01) C07D 401/12 (2006.01) C07D 405/04 (2006.01) C07D 413/12 (2006.01)

Patent

CA 1254561

ABSTRACT OF THE DISCLOSURE A process for preparing 3-(aminoalkylamino- carbonylmethoxy)-5-phenylpyrazole compounds correspond- ing to the formula: Image in which R1, R2, R5, R6, R7, and R8 and R9 may be hydrogen or lower alkyl groups, or R5 with R6 and/or R8 with R9 may also form specified cyclic groups, R3 and R4 may be hydrogen, halogen, lower alkyl, lower alkoxy, trifluoromethyl, nitro, hydroxy or alkylene dioxy, and Z represents an alkylene chain or the 2-hydroxypropyl- ene chain. The compounds possess pharmacological, in particular antiarrhythmic, properties. -50-

485571

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