3-aminoindazoles

Details 3-aminoindazoles 3-aminoindazoles

C - Chemistry, Metallurgy

07

D

C07D 231/56 (2006.01) A61K 31/416 (2006.01) C07D 401/12 (2006.01) C07D 405/04 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2570264

Novel 3-aminoindazoles of formula (I) are SGK-inhibitors and can be used for treating SGK-related diseases and illnesses such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, and generally any type of fibroses and inflammatory processes.

L'invention concerne de nouveaux 3-aminoindazoles de formule (I), qui sont des inhibiteurs de la kinase dépendante du sérum humain et du glucocorticoïde (SGK) et peuvent s'utiliser pour traiter des affections induites par SGK et des pathologies telles que le diabète, l'obésité, le syndrome métabolique (dyslipidémie), l'hypertonie systémique et pulmonaire, les maladies cardio-vasculaires et des maladies rénales et de manière générale, tout type de fibroses et de processus inflammatoires.

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