3- and 6-quinolines with n-attached heterocyclic cgrp...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 471/20 (2006.01) A61K 31/4745 (2006.01) A61K 31/496 (2006.01) A61K 31/499 (2006.01) A61K 31/551 (2006.01) A61P 25/06 (2006.01)

Patent

CA 2734168

Compounds of Formula (I): (where variables R1A, R1B, R2, R3, R4, A, and Z are as defined herein) which are useful as antagonists of CGRP receptors, and useful in the treatment or prevention of diseases in which CGRP receptors are involved, such as headache, and in particular migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP receptors are involved.

L'invention porte sur des composés de Formule (I) : (dans laquelle les variables R1A, R1B, R2, R3, R4, A et Z sont telles que définies ici) qui sont utiles comme antagonistes de récepteurs de peptides associés au gène de la calcitonine (CGRP), et qui sont utiles dans le traitement ou la prévention de maladies dans lesquelles des récepteurs de peptides associés au gène de la calcitonine sont impliqués, telles que les maux de tête, et, en particulier la migraine et l'algie vasculaire de la face. L'invention porte également sur des compositions pharmaceutiques comprenant ces composés et sur l'utilisation de ces composés et de ces compositions dans la prévention ou le traitement des maladies dans lesquelles des récepteurs CGRP sont impliqués.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

3- and 6-quinolines with n-attached heterocyclic cgrp... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3- and 6-quinolines with n-attached heterocyclic cgrp..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3- and 6-quinolines with n-attached heterocyclic cgrp... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2067286

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.