3-anilino-2-cycloalkenone derivatives

Details 3-anilino-2-cycloalkenone derivatives 3-anilino-2-cycloalkenone derivatives

C - Chemistry, Metallurgy

07

C

C07C 225/20 (2006.01) A61K 31/135 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) C07C 225/22 (2006.01) C07D 211/86 (2006.01) C07D 213/38 (2006.01) C07D 215/12 (2006.01) C07D 295/116 (2006.01) C07D 307/20 (2006.01)

Patent

CA 2295106

A 3-anilino-2-cycloalkenone derivative of the formula (I): (see formula I) wherein, R1 represents a C1 - to C8 alkyl group, which may have a substituent, except for a methyl group, a C3 to C7 cycloalkyl group, a 3-tetrahydrofuryl group, an Z-indanyl group, etc., R2 represents a C1 to C4 alkyl group, R3 represents a hydrogen atom, a C1 to C5 alkyl group, which may have a substituent, a C3 to C7 cycloalkyl group, etc., R4 represents a hydrogen atom, a C1 to C5 alkyl group, which may have a substituent, a halogen atom, etc., R5, R6, R7, and R8 independently represent a hydrogen atom, a C1 to C5 alkyl group, which may have a substituent, etc., X represents -(CR11R12)n-, wherein n is 0 to 2, R11 and R12 independently represent a hydrogen atom, a C1 to C5 alkyl group, which may have a substituent, etc. or -NR13- wherein R13 represents a hydrogen atom or a C1 to C5 alkyl group, which may have a substituent, and its optical isomers or their pharmaceutically acceptable salts or their hydrates or solvates.

L'invention concerne des dérivés de la 3-anilino-2-cycloalcénone, représentés par la formule générale (I), dans laquelle R1 représente alkyle C1-8 (à l'exclusion du méthyle) éventuellement substitué, cycloalkyle C3-7, 3-tétrahydrofuryle, 2-indanyle, etc.; R2 représente alkyle C1-4; R3 représente H, alkyle C1-5 éventuellement substitué, cycloalkyle C3-7, etc.; R4 représente H, alkyle C1-5 éventuellement substitué, halogéno, etc.; R5, R6, R7 et R8 représentent indépendamment H, alkyle C1-5 éventuellement substitué, etc.; et X représente -(CR11R12)n- (où n est compris entre 0 et 2, et où R11 et R12 représentent indépendamment H, alkyle C1-5 éventuellement substitué, etc.) ou NR13 (où R13 représente H ou alkyle C1-5 éventuellement substitué); ainsi que leurs isomères optiques, leurs sels pharmaceutiquement acceptables, leurs hydrates et leurs solvates.

Affiliated with

Also associated with

Rating

3-anilino-2-cycloalkenone derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-anilino-2-cycloalkenone derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-anilino-2-cycloalkenone derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1418643