C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/24 (2006.01) A61K 31/439 (2006.01) A61P 25/04 (2006.01) A61P 25/32 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2522323
The subject invention relates to 3-azabicyclo[3.2.1]octane derivatives, pharmaceutical compositions comprising such derivatives and methods of using such derivatives to treat disease states, disorders and conditions mediated by opioid receptors. The subject invention also particularly relates to using such derivatives to treat certain disorders and conditions, for example irritable bowel syndrome, drug addiction, depression, anxiety, schizophrenia and eating disorders, among others. (see above formula)
La présente invention se rapporte à des dérivés de 3-azabicyclo[3.2.1]octane, à des compositions pharmaceutiques les comportant, et à des procédés d'utilisation de dérivés de ce type dans le traitement d'états pathologiques, de troubles et d'affections à médiation par les récepteurs opioïdes. L'invention se rapporte également et plus spécialement à l'utilisation de dérivés de ce type dans le traitement de certains troubles et affections, par exemple le syndrome du côlon irritable, la toxicomanie, la dépression, l'anxiété, la schizophrénie et les troubles de l'alimentation, entre autres.
Bashore Crystal Gayle
Coe Jotham Wadsworth
Mchardy Stanton Furst
Pfizer Products Inc.
Torys Llp
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