C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 237/28 (2006.01) A61K 31/502 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2675621
The invention relates to chemical compounds of formula (I): Formula (I), or pharmaceutically acceptable salts thereof which possess CSF 1R kinase inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti cancer effect in a warm blooded animal such as man.
L'invention porte sur des composés chimiques de formule (I) : Formule (I) ou des sels pharmaceutiquement acceptables de ceux-ci, qui possèdent une activité inhibitrice de la CSF 1R kinase et sont, par conséquent, utiles pour leur activité anti-cancer et ainsi dans des procédés de traitement du corps humain ou animal. L'invention porte également sur des procédés de fabrication desdits composés chimiques ; sur des compositions pharmaceutiques les contenant ; et sur leur utilisation dans la fabrication de médicaments destinés à être utilisés dans la production d'un effet anti-cancer chez un mammifère à sang chaud tel que l'homme.
Dakin Leslie
Ogoe Claude Afona
Scott David
Zheng Xiaolan
Astrazeneca Ab
Fetherstonhaugh & Co.
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