C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/228, 260/294
C07D 213/85 (2006.01) A61K 31/44 (2006.01)
Patent
CA 1242443
ABSTRACT OF THE DISCLOSURE Novel 5-acyl-2-(1H)pyridinones and their use as cardiotonic agents. Typical of the compounds is 5-n- pentanoyl-1,2 dihydro-6-methyl-2-oxo-3-pyridinecarbo- nitrile which is prepared by condensing anionic cyano acetamide with 3-[(dimethylamino)methylenyl]-2,4-octanedione in an inert organic solvent.
452888
Dage Richard C.
Jones Winton D.
Schnettler Richard A.
Merrell Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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