3-cyano-quinoline derivatives with antiproliferative activity

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 498/08 (2006.01) A61K 31/4748 (2006.01) A61P 35/00 (2006.01) C07D 215/54 (2006.01)

Patent

CA 2549728

The present invention concerns the compounds of formula (I) the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof. Compounds of formula (I) inhibit tyrosine kinase enzymes.

L'invention concerne les composés de formule (I), les formes <I>N</I>-oxide, les sels d'addition acceptables sur le plan pharmaceutique ainsi que les formes stéréochimiquement isomériques de ceux-ci. Les composés de formule (I) inhibent les tyrosine kinases.

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