3-cyanoalkyl- and 3-hydroxyalkylindoles and use thereof

C - Chemistry – Metallurgy – 07 – D

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C07D 209/10 (2006.01) A61K 31/40 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2729057

The present application relates to novel 3-cyanoalkyl- and 3-hydroxyalkyl- substituted indole derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of cardiovascular diseases.

La présente invention porte sur de nouveaux dérivés d'indole à substitution 3-cyanoalkyle- et 3-hydroxyalkyle-, sur des procédés pour les préparer, sur leur utilisation à titre individuel ou en combinaison pour le traitement et/ou la prévention de maladies, ainsi que sur leur utilisation pour préparer des médicaments destinés au traitement et/ou à la prévention de maladies, en particulier au traitement et/ou à la prévention de maladies cardiovasculaires.

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