3-cyclyl-2- (4-sulfamo yl-phenyl) -n-cyclyl-propionamide...

Details 3-cyclyl-2- (4-sulfamo yl-phenyl) -n-cyclyl-propionamide... 3-cyclyl-2- (4-sulfamo yl-phenyl) -n-cyclyl-propionamide...

C - Chemistry, Metallurgy

07

D

C07D 211/62 (2006.01) C07D 213/75 (2006.01) C07D 239/42 (2006.01) C07D 241/04 (2006.01) C07D 241/20 (2006.01) C07D 277/46 (2006.01) C07D 277/82 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2623686

The present invention provides compounds of the formula (I); which are activators of glucokinase activity and, thus, may be employed as therapeutic agents for the treatment of glucokinase mediated conditions. Accordingly, the compounds of formula (I) may be employed for the prevention and the treatment of impaired glucose tolerance, type 2 diabetes and obesity.

La présente invention concerne des composés représentés par la formule générale (I), qui sont des activateurs de l'activité de la glucokinase et qui, par conséquent, peuvent être utilisés comme agents thérapeutiques pour le traitement de troubles induits par la glucokinase. Ainsi, les composés représentés par la formule générale (I) peuvent être utilisés pour la prévention et le traitement d'une tolérance au glucose perturbée, du diabète de type 2 et de l'obésité.

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