3-deoxy-3-descladinose derivatives of erythromycins a and b

C - Chemistry – Metallurgy – 07 – H

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C07H 17/08 (2006.01) A61K 31/70 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2235681

A compound selected from groups (I), (II), and (III), wherein A, B, V, W, X and R8 are specifically defined; pharmaceutical compositions thereof; a method of treating or preventing bacterial infections by administering therapeutically effective pharmaceutical compositions thereof; and a process for the preparation thereof.

La présente invention concerne un composé sélectionné dans le groupe auquel appartiennent les formules générales (I), (II) et (III). Dans ces formules générales, A, B, V, W, X et R?8¿ sont définis de façon spécifique. L'invention concerne également des compositions pharmaceutiques réalisées à partir de ces dérivés. L'invention concerne en outre une méthode de traitement ou de prévention des infections bactériennes par administration de telles compositions pharmaceutiques thérapeutiquement efficaces. L'invention concerne enfin un procédé de préparation de ces dérivés.

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