C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/20 (2006.01) C07H 19/04 (2006.01) C07H 19/10 (2006.01) C09B 57/00 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2265019
Disclosed are 3'-deoxyribonucleotide derivatives represented by the following general formula [I]: Q-V-(CH2)n-NH-R [I] wherein Q represents a 3'-deoxyribonucleotide residue, n represents an integer not less than 4, V represents -C~C- or -CH~CH-, and R represents a fluorescent group. The above 3'-deoxyribonucleotide derivatives are derivatives with improved rates for incorporation using RNA polymerases, which are useful as terminators in the DNA sequence determination methods utilizing RNA polymerases.
Fujio Kazunari
Hayashizaki Yoshihide
Ozawa Kaori
Dennison Associates
Hayashizaki Yoshihide
Nippon Genetech Co. Ltd.
The Institute Of Physical And Chemical Research
Wako Pure Chemical Industries Ltd.
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