C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/08 (2006.01) A61K 31/70 (2006.01) C07H 23/00 (2006.01)
Patent
CA 2253451
Novel 3-descladinose-2,3-anhydroerythromycin compounds and pharmaceutically acceptable salts and esters thereof having antibacterial activity selected from the group consisting of: (a) (I), (b) (II), (c) (III), and (d) (IV), pharmaceutical compositions comprising a therapeutically effective amount of a compound of formulas (I)-(IV) of the invention in combination with a pharmaceutically acceptable carrier, as well as a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of formulas (I)- (IV) of the invention.
L'invention concerne de nouveaux composés de la 3-descladinose-2,3-anhydro-érythromycine, leurs sels et leurs esters pharmaceutiquement acceptables, ayant une activité anti-bactérienne, choisis dans le groupe constitué de a) (I), b) (II), c) (III) et d) (IV); des compositions pharmaceutiques contenant une quantité thérapeutiquement efficace d'un composé de formule (I)-(IV) associé à un support pharmaceutiquement acceptable; ainsi qu'une méthode permettant de traiter les infections bactériennes en administrant à un mammifère une composition pharmaceutique contenant une quantité thérapeutiquement efficace d'un composé de formule (I)-(IV).
Chu Daniel T.
Elliott Richard L.
Griesgraber George W.
Or Yat Sun
Pireh Daisy
Abbott Laboratories
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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