3-descladinosyl-6-o-carbamoyl and 6-o-carbonoyl macrolide...

C - Chemistry – Metallurgy – 07 – H

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C07H 17/08 (2006.01) A61K 31/70 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2487918

3-Descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents of the formula: (I) wherein R1, W, R3, R4, R5, R6, X, X', and Z are as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.

L'invention concerne des agents antibactériens macrolides 3-descladinosyl-6-O-carbamyle et 6-O-carbonyle représentés par la formule (I) dans laquelle R?1¿, W, R?3¿, R?4¿, R?5¿, R?6¿, X, X', et Z sont tels que définis dans le descriptif et les substituants ont les significations indiquées dans le descriptif. Ces composés sont utiles en tant qu'agents antibactériens.

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