3-(dihydro-1h-pyrazolo [4,3-d]...

Details 3-(dihydro-1h-pyrazolo [4,3-d]... 3-(dihydro-1h-pyrazolo [4,3-d]...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 15/10 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2664940

This invention relates to novel 3-(dihydro-lH-pyrazolo[4,3-d]pyrimidin-5-yl)-4- propoxybenzenesulfonamide compounds, their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering inhibitors of cyclic guanosine 3',5'- monophosphate specific phosphodiesterase (cGMP- specific PDE), in particular PDE5.

L'invention concerne de nouveaux composés 3-(dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-propoxybenzènesulfonamide, leurs dérivés, sels, solvates et hydrates pharmaceutiquement acceptables de ceux-ci. L'invention concerne également des compositions comprenant un composé de l'invention et l'utilisation de telles compositions dans des procédés de traitement de maladies et affections qui sont traitées de façon bénéfique en administrant des inhibiteurs de phosphodiestérase spécifiques du guanosine 3',5'-monophosphate cyclique (PDE spécifique du GMPc), en particulier la PDE5.

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