3'-epimeric k-252a derivatives

Details 3'-epimeric k-252a derivatives 3'-epimeric k-252a derivatives

C - Chemistry, Metallurgy

07

D

C07D 498/22 (2006.01) A61K 31/55 (2006.01) C07D 209/00 (2006.01) C07D 273/00 (2006.01) C07D 307/00 (2006.01) C07H 5/06 (2006.01) C07H 7/06 (2006.01)

Patent

CA 2315953

Compounds defined by general structure (II) are disclosed. These compounds display pharmacological activities, including inhibition of tyrosine kinase activity and enhancement of the function and/or survival of trophic factor responsive cells, e.g., cholinergic neurons.

L'invention concerne des composés définis par la formule générale (II). Ces composés présentent une action pharmacologique dans la mesure où ils inhibent l'activité de tyrosine kinase et favorisent la fonction et/ou la survie de cellules réagissant au facteur trophique, par exemple les neurones cholinergiques.

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