3'-expression enhancing fragments and method

Details 3'-expression enhancing fragments and method 3'-expression enhancing fragments and method

C - Chemistry, Metallurgy

12

P

195/1.2, 195/1.2

C12P 21/00 (2006.01) C07H 15/12 (2006.01) C07K 14/55 (2006.01) C12N 9/86 (2006.01) C12N 15/00 (2006.01) C12N 15/67 (2006.01) C12N 15/70 (2006.01)

Patent

CA 1275954

Abstract of the Disclosure The invention concerns a method for extending the half-life of RNAs. The half-life extension is conferred upon the RNA by a co- transcribed positive retroregulatory element which is ligated to the 3' end of the DNA sequence coding the RNA. RNAs having an extended half-life conferred by a co-transcribed positive retroregulatory element are also claimed.

488396

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