3-fluoro-piperidines as nmda/nr2b antagonists

Details 3-fluoro-piperidines as nmda/nr2b antagonists 3-fluoro-piperidines as nmda/nr2b antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/506 (2006.01) A61P 25/16 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2527093

Compounds represented by Formula (I) or pharmaceutically acceptable salts thereof, are effective as NMDA NR2B antagonists useful for treating conditions such as, for example, Parkinson~s disease, Alzheimer~s disease, migraine, epilepsy and pain.

L'invention concerne des composés représentés par la formule (I) ou leurs sels pharmaceutiquement acceptables, lesquels sont efficaces en tant qu'antagonistes de NMDA NR2B utiles pour traiter des états tels que, par exemple, la maladie de Parkinson, la maladie d'Alzheimer, la migraine, l'épilepsie et la douleur.

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