3-fluorobenzodiazepines

Details 3-fluorobenzodiazepines 3-fluorobenzodiazepines

C - Chemistry, Metallurgy

07

D

260/240.3

C07D 243/24 (2006.01)

Patent

CA 1100960

ABSTRACT OF THE DISCLOSURE Novel 3-fluoro-2,3-dihydro-1H-1,4-benzodiazepin-2-ones of the formula I Image (I) wherein R1 is H or alkyl of 1-4 carbon atoms; R2 is phenyl or mono- halophenyl; R3 is F, Cl, Br or NO2, and physiologically acceptable acid addition salts thereof are provided herein. These compounds are central nervous system depressants. They may be prepared by certain specified reactions using, as an essential starting material, certain specified bezodiazepine derivatives.

242041

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