3-heteroarylalkyl substituted gaba analogs

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 333/24 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61P 19/02 (2006.01) A61P 25/08 (2006.01) A61P 25/24 (2006.01) C07D 207/327 (2006.01) C07D 207/337 (2006.01) C07D 307/54 (2006.01)

Patent

CA 2371089

The invention is a novel series of compounds which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.

L'invention concerne une nouvelle série de composés qui sont utiles pour le traitement de l'épilepsie, des crises d'évanouissement, des troubles neurodégénératifs, de la dépression, de l'anxiété, de la panique, de la douleur, des troubles neuropathologiques, des troubles gastrointestinaux, du syndrome du côlon irritable (IBS), et de l'inflammation, notamment l'arthrite. L'invention concerne en outre une composition pharmaceutique contenant un composé de l'invention, ainsi que des méthodes de préparation desdits composés et de nouveaux intermédiaires utiles dans la préparation des composés définitifs.

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