3-indolepyruvic acid derivatives and pharmaceutical use thereof

Details 3-indolepyruvic acid derivatives and pharmaceutical use thereof 3-indolepyruvic acid derivatives and pharmaceutical use thereof

C - Chemistry, Metallurgy

07

D

167/240, 260/306

C07D 209/18 (2006.01) A61K 31/405 (2006.01) C07D 403/06 (2006.01)

Patent

CA 1328658

ABSTRACT 3-indolepyruvic acid and derivatives thereof in the form of salts, esters and amides are compounds pharmaceutically active as agents for antagonising disturbances of the central nervous system, such as epilepsy, cerebral ischemia, ictus and Alzheimer's disease, through a mechanism of action which raises the level of kynurenic acid in the brain.

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