3-indolyl-tertiary butylaminopropanols

Details 3-indolyl-tertiary butylaminopropanols 3-indolyl-tertiary butylaminopropanols

C - Chemistry, Metallurgy

07

D

260/300, 260/319

C07D 209/10 (2006.01) C07D 209/14 (2006.01) C07D 403/12 (2006.01)

Patent

CA 1116598

Abstract of the Disclosure 1-Phenoxy-3[(3-indoly)-tert.-butyl]amino-2-propanols and related 1-aryloxy compounds bearing various ring substituents such as alkyl, cyano, amino, carboxanido, trifluoromethyl, and various heterocyclic groups such as 1-pyrrolyl are antihypertensive agents having vasodilator and adrenergic .beta.-receptor blocking action. Preferred compounds bear an ortho-substituent in the phenoxy group, and most preferably the methyl group.

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