3-indolylpiperidines

Details 3-indolylpiperidines 3-indolylpiperidines

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/445 (2006.01) C07D 491/04 (2006.01) C07D 491/056 (2006.01)

Patent

CA 2147451

3-Indolylpiperidines of the formula I (see formula I) wherein R1. R2. R3 and R4 are in each case independently of one another H, A, OH, OA, F, Cl, Br, I, CN, CF3, COON, CONH2, CONHA, CONA2 or COOA, or R1 and R2 and also R3 and R4 in each case together are also methylenedioxy, R5 is H or OH, R6 is H or R5 and R6 together are also a bond, A is alkyl having 1 to 6 C atoms and n is 2, 3, 4, 5 or 6, and to their physiologically acceptable salts, exhibit action on the central nervous system, in particular dopamine-agonistic or dopamine-antagonistic action.

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