C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/55 (2006.01) C07D 223/12 (2006.01) C07D 243/08 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2266759
The present invention relates to compounds of the formula (1) (see formula I) useful as inhibitors of matrix metalloproteinase. Pharmaceutical compositions containing said compounds and uses thereof are also claimed herein.
L'invention concerne certains dérivés 3-mercaptoacétylamino-1,5-substitué-2-oxo-azépane, utilisés comme inhibiteurs de métalloprotéinase matrice. L'invention concerne également des compositions pharmaceutiques contenant lesdits composés et des méthodes de traitement de différents états pathologiques répondant à l'inhibition de métalloprotéinase matrice.
Beight Douglas W.
Burkhart Joseph P.
Dharanipragada Ramalinga M.
Flynn Gary A.
Janusz Michael J.
Aventisub II Inc.
Hoechst Marion Roussel Inc.
Osler Hoskin & Harcourt Llp
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