3-methyl-sulphur-containing-methylene-1-lower...

Details 3-methyl-sulphur-containing-methylene-1-lower... 3-methyl-sulphur-containing-methylene-1-lower...

C - Chemistry, Metallurgy

07

D

260/285

C07D 215/22 (2006.01) C07D 215/18 (2006.01) C07D 215/233 (2006.01) C07D 215/26 (2006.01) C07D 215/36 (2006.01) C07D 215/56 (2006.01)

Patent

CA 1146943

ABSTRACT OF THE DISCLOSURE Novel quinolone compounds having therapeutic activity as hypertensive agents correspond to the general formula: Image wherein n is 0, 1 or 2; R1 is lower alkyl; and R3 is hydrogen, lower alkyl, methoxy, methylthio, halo or trifluoromethyl. They may be prepared for example, by reacting a compound of the above structure but having a group -CH2X, in which X is a leaving group, at the 3- position, with methylthiolate or methanesulphinate anion.

386485

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