3-methylidenyl-2-indolinone modulators of protein kinase

Details 3-methylidenyl-2-indolinone modulators of protein kinase 3-methylidenyl-2-indolinone modulators of protein kinase

C - Chemistry, Metallurgy

07

D

C07D 209/34 (2006.01) A61K 31/404 (2006.01) A61K 31/437 (2006.01) A61K 31/4439 (2006.01) A61K 31/5377 (2006.01) C07D 209/04 (2006.01) C07D 401/10 (2006.01) C07D 405/06 (2006.01) C07D 409/10 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2383623

The present invention relates to novel 3-methylidenyl-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

L'invention concerne de nouveaux composés 3-méthylidényl-2-indolinone ainsi que leurs sels physiologiquement acceptables et leurs promédicaments. Ces composés modulent l'activité des protéines kinases et par conséquent sont supposés convenir à la prévention et au traitement des troubles cellulaires liés à la protéine kinase, comme par exemple le cancer.

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