3- or 4-monosubstituted phenol and thiophenol derivatives...

C - Chemistry – Metallurgy – 07 – D

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C07D 309/06 (2006.01) A61K 31/55 (2006.01) A61P 25/06 (2006.01) C07D 295/12 (2006.01) C07D 295/14 (2006.01) C07D 309/08 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2565852

The invention relates to 3- or 4-monosubstituted phenol and thiophenol derivatives of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. Said 3- or 4-monosubstituted phenol and thiophenol derivatives are H3 ligands and are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

L'invention concerne des dérivés de phénol et de thiophénol 3- ou 4-monosubstitués de formule (1) et des procédés de préparation associés, des intermédiaires utilisés dans la préparation de ceux-ci, des compositions les contenant et l'utilisation desdits dérivés. Lesdits dérivés de phénol et de thiophénol 3- ou 4-monosubstitués sont des ligands H¿3? et sont utiles dans de nombreuses maladies et de nombreux troubles et états, en particulier des maladies, troubles et états de type inflammatoires, allergiques et respiratoires.

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